Is serum phosphorus control related to parathyroid hormone control in dialysis patients with secondary hyperparathyroidism?

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Is serum phosphorus control related to parathyroid hormone control in dialysis patients with secondary hyperparathyroidism?

BACKGROUND Elevated serum phosphorus (P) levels have been linked to increased morbidity and mortality in dialysis patients with secondary hyperparathyroidism (SHPT) but may be difficult to control if parathyroid hormone (PTH) is persistently elevated. We conducted a post hoc analysis of data from an earlier interventional study (OPTIMA) to explore the relationship between PTH control and serum ...

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Serum phosphorus reduction in dialysis patients treated with cinacalcet for secondary hyperparathyroidism results mainly from parathyroid hormone reduction

BACKGROUND The calcimimetic cinacalcet lowers parathyroid hormone (PTH), calcium (Ca) and phosphorus (P) in dialysis patients with secondary hyperparathyroidism (SHPT). We explored serum P changes in dialysis patients treated with cinacalcet, while controlling for vitamin D sterol and phosphate binder (PB) changes, based on data from the pan-European observational study ECHO. METHODS Patients...

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Relationship between Basal Metabolic Rate and Serum Parathyroid Hormone and Body Composition in Women with Secondary Hyperparathyroidism

Introduction: Several factors including fat free mass and fat mass can affect Basal Metabolic Rate (BMR) as the largest component of daily energy demand. The aim of the current cross-sectional study was to compare BMR in women with secondary hyperparathyroidism and healthy women and to evaluate its relationship with serum Parathyroid Hormone (PTH), fat free mass and fat mass in these subjects. ...

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Effect of vitamin C on parathyroid hormone in hemodialysis patients with mild to moderate secondary hyperparathyroidism.

INTRODUCTION In end-stage renal disease, there is a high incidence of secondary hyperparathyroidism. It is proposed that increasing vitamin C levels by dietary supplementation results in a decrease of parathyroid hormone (PTH) in vitamin C-deficient hemodialysis patients with secondary hyperparathyroidism. The aim of this study was the evaluation of vitamin C administration for reduction of ser...

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The parathyroid hormone-related peptide (PTHrP) has been shown to be the major pathogenic factor to humoral hypercalcemia of malignancy (HHM). The presence of PTHrP in many normal tissues and in normal or abnormal parathyroids has been described in literature and its role has been investigated. PTHrP release from parathyroid cells into the extracellular space has been demonstrated to depend on ...

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ژورنال

عنوان ژورنال: BMC Nephrology

سال: 2012

ISSN: 1471-2369

DOI: 10.1186/1471-2369-13-76